The antibacterial peptide library (antimicrobial peptides) is one of the Amoy biovhemistry (Top) research team to build characteristic peptide library, peptide library is one of the few domestic varieties, high quality and reasonable price, the collection of nearly twenty kinds of antibacterial peptides, and has obtained the customer high praise. Top will continue to tap more antimicrobial peptides, is committed to serving the domestic scientific research institutions and institutions.

1 the concept and classification of antimicrobial peptides

Antimicrobial peptide (antimicrobial peptides) is a general term for peptides with antimicrobial activity. G. B o m of Sweden in 1975 a n et al from hyalophora Cecropia pupae (Hyatophoracecropia) induced by isolated bactericidal peptide, and named it cecropin. Since then, many antimicrobial peptides have been isolated and purified. The primary structure and gene sequence of some antimicrobial peptides were determined. In 80s, studies on antimicrobial peptides were concentrated on large insects. Since 90s, it has been widely used in the field of immunology and molecular biology, while it has been extended to some small insects and other invertebrate and vertebrate. Up to now, a lot of antibacterial proteins and peptides have been found in different animal tissues, and the structure of more than 70 kinds of antibacterial peptides has been determined.

According to the structure of antibacterial peptides, which can be divided into 5 categories: (1) single free cysteine residues of alpha helix, or by random coil connected to the two section of alphahelix peptide; (2) antibacterial peptide rich in certain amino acid residues but not containing cysteine residues; (3) 1 containing two disulfide bonds of antibacterial peptides; antibacterial peptide (4) 2 or more than 2, two disulfide bonds with beta folding structure; (5) large polypeptides from other known functional derivative peptides with antimicrobial activity to. The first isolated Cecropins and Magainins isolated from Xenopus laevis belong to the first class of antimicrobial peptides, which are commonly known as Cecropin antimicrobial peptides.